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'=  \*Function of Liver in Material Metabolism ++ H 0 0޽h ? 3ur3f}}y___PPT10Y+D='  = @B +   0L0 4x(  4 4 s * _E   *6GHI` 4 Z@ ?" :c,$ 0 >|_u0 |SvTbNR0 |u_ ( vF2 # 4 4 Z( ?"/ ,$ 0 hV~QۏLN|N"_&3 H 4 0޽h ? 1?Tz<([ӥaG|I A ___PPT10! +ՁD'  = @B DP' = @BA?%,( < +O%,( < +D{' =%(D#' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*4%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*4D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*4D' =%(D' =%(DT' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*4%(D' =-6B'blinds(horizontal)*<3<*4+p+0+40 ++0+40 +  0L0 8N(  8x 8 c $<    <   8 c $< < ] <  *ppqrsH 8 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D='  = @B +   0L0 ZR<(  <x < c $t <  G~g  <   < c $t)< 2Y<$ 0 <  0$%&b < Z ?" :\O(u(W{|vmS08T6e0Tb0RNЏGWwQ g͑\O(u0D8vFx2g3c MM//H < 0޽h ? 1?Tz<%UӥaG|___PPT10.+Dv'  = @B D1' = @BA?%,( < +O%,( < +Dh' =%(D' =%(DX' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*<%(D' =-6B+checkerboard(across)*<3<*<DX' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*<a%(D' =-6B+checkerboard(across)*<3<*<a+8+0+<0 +  0L0 @(  @ @ c $I<   f <$  0  <   @ c $0K< bY<$  0 <  *"#$H @ 0޽h ? 1?Tz<%UӥaG| ___PPT10.+/.DL'  = @B D' = @BA?%,( < +O%,( < +D>' =%(%(D' =%(D>' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-m6Bbox(in)*<3<*@D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-6B%strips(downRight)*<3<*@DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-6B%strips(downRight)*<3<*@D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-6B%strips(downRight)*<3<*@DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@3%(D' =-6B%strips(downRight)*<3<*@3D' =%( DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@36%(D' =-6B%strips(downRight)*<3<*@36DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@6Q%(D' =-6B%strips(downRight)*<3<*@6QD' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@QT%(D' =-6B%strips(downRight)*<3<*@QTDR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@Tr%(D' =-6B%strips(downRight)*<3<*@Tr+p+0+@0 ++0+@0 +   0L0 D(  D D s *o<   *<$D 0  <   D c $lt< /7Y<$  0 <  &xW | }H D 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D='  = @B +  0L0  Hp(  Hx H c $<  7g  <   H c $< ,<$  0 <   0EH H 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D='  = @B +c  0L0 &0L(  L~ L s *<  du  <   L s *ȭ<  I <$  0 <  (yMNOP* L ZP< ?" 5 ,$ 0 ^* ;Ne_uirlS # H L 0޽h ? 1?Tz<%UӥaG|  ___PPT10 .+IxD ' < = @B D ' = @BA?%,( < +O%,( < +D|' =%(%(D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*L %(D' =-6B%strips(downRight)*<3<*L DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*L =%(D' =-6B%strips(downRight)*<3<*L =D{' =%(D#' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*L%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*LD' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*L+p+0+L0 ++0+L0 +0  0L0 ?7@P(  P P H<  zf   <   P  `< ?"  +  U#Biotransformation Function of Liver$$ H P 0޽h ? 3ur3f}}y___PPT10Y+D='  = @B +A  0L0 PHPT(  Tx T c $<  Z %j  <   T c $< ]R  <  (yMNOPF F  T p m r T  f jJ?? #,$D 02 T  `=  ?? F  ,$D 0 fQn'`Yo }0{|I{" 0 c  2 T  `<  ?? f ,$D 0 fYn'`Yoir0kirI{" 0 c   T T= ?" t  ^ ^%{Qir(& vF" H T 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D='  = @B + 0L0 \T`X(  X X T=  ??w ,$ 0  uirlSvaIN [SOQv^%{Qir(ۏLlS OvQmp;m (inactivate) bk(detoxicate)f:N͑v/fSOُNir(vn㉦^XR fNcQSOY0  0e0 g3c cc ccg3P  5 0q6 X T00=  ??j,7,$ 0 T uirlSv;N:W@b /f;NhV[ FO(W00ÀSTv_N gN[uirlSR 0J 0 0x g3 c + 0q6F X T$=  ??f ,$  0  ; vuirlS\O(u`"k\O(u&0g3$H X 0޽h ? 1?Tz<%UӥaG|. & ___PPT10 +חoDB '  = @B D ' = @BA?%,( < +O%,( < +D*' =%(%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*X%(D' =-6B-randombar(horizontal)*<3<*XD' =%(D' =%(DV' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*X%(D' =-6B)randombar(vertical)*<3<*XD' =%(D' =%(DD' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*X%(D' =-s6Bwipe(left)*<3<*X++0+X0 ++0+X0 ++0+X0 +<   0L0 p\~(  \~ \ s *R=  'g  =   \ s *V=  =  (789d \ Z`= ?"C7o ,$D 0 .* gNir(~Ǐ,{NvS^sSSz)RcQSOY0<0vffZcc  \ Zq= ?" dB,$D 0 h* ir(sSO~Ǐ,{NvS^T g'`9eSN N'Y _{NgNg'`f:_vir(~T, sS,{NvS^ Mbg~cQ0,58vffn5c% H \ 0޽h ? 1?Tz<%UӥaG|___PPT10+[D*'  = @B D' = @BA?%,( < +O%,( < +D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*\%(D' =-6B-randombar(horizontal)*<3<*\D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*\%(D' =-6B-randombar(horizontal)*<3<*\+p+0+\0 ++0+\0 +_  0L0 nf`(  ` ` <=  Zb  =  . `  = 0e0ejJ C"?]Y =  *H ` 0޽h ? 3ur3f}}y___PPT10Y+D='  = @B +] 0L0 \Td(  d d H=  (?"7JY  .j; W,gyrp vco;m'lRP[ vQ-NN*N'lSP[ReQ^irRP[-N SN'lSP[؏S:N4l EeSy:NmTR'lSv0v08200cc'c g35pH d 0޽h ? 3ur3f}}___PPT10i._g+D='  = @B +  0L0 @8h(  h h C $A RUS'lv|T,$D  0 h Hv??"gw@ 0 0" h Hv??"w@ 0 0` h s *v"} h T= v??"p  0 J$0G f  h H= "n  0 Xv U_$0G ,G B h s *޽h ? 1?Tz<%Uӥf|___PPT10+EpUhD' = @B D_' = @BA?%,( < +O%,( < +D' =%(%(D' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*h%(D' =+4 8?dCB2/3*#ppt_wBCB#ppt_wB*Y3>B ppt_w<*hD' =+4 8?dCB2/3*#ppt_hBCB#ppt_hB*Y3>B ppt_h<*h+ 0L0  l(  l l N=  ?"7 L&0 2G+Y x l N=  ?" ,$D 0 " NirSirbs'lSir >NOh0u(Z2g3 cg3c xB l BD?"P l  ` A ??"    l  `= ?"F <  l  `? ?"   J"  l  `x? ?" `   P [(lWZ" b l JA޽h ?10+ 1?Tz<%UӥaG|y___PPT10Y+D='  = @B + 0L0 &p(  px p <A ??i  p H? >B# nYspvu irlSǏ z( 0 g  p Hv??"gw@ 0 0" p Hv??"w@ 0 0` p s *v"} p T(? v??"p  0 J$0G f  p H2? "n  0 Xv U_$0G ,G B p s *޽h ? ffD3fy___PPT10Y+D='  = @B +  0L0   t(  t t H?? ?"d X2. ~|SOUS'lSv| US'lSv( monoamine oxidase, MAO)N 0  00x c g3,  t H5? ?"}7w  X[(WMO~|SOQ> u(g3c  t HV? ?"p7  , PSvS^ PS{|'lS1(lWubv^v u( (cg3cg3 cg3 'F    t    t T+B#style.visibility<*|%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*|D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*|D' =%(D' =%(DX' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*|%(D' =-6B+checkerboard(across)*<3<*|+p+0+|0 ++0+|0 + 0L0 RJ(    N? ?"PdF ,$  0 `~T[aQ+T gW0Wb(lWvoir0kirbo }GWSSu~TS^ ,10 uZ21c 1 SS  N? ?"c d# ,$  0 l~TBRa|x0kxx07u0u(lx0YNpW02uWI{ir(bWV f70 uZx2cg3c#c 7 <  Z? ?" ,$  0 pV ~TS^4G !g ! H  0޽h ? 3ur3f}}  ___PPT10 ._a>D+KPD '  = @B D ' = @BA?%,( < +O%,( < +D' =%(%(D' =%(DN' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-}6B!slide(fromLeft)*<3<*D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B%strips(downRight)*<3<*D' =%(D' =%(DP' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B#strips(downLeft)*<3<*++0+0 ++0+0 ++0+0 +"  0L0 ? 7  (  x  c $HA   A    s *A 7"<$ 0 A  *qklm  c ,Awy1T,$D  0  c ,A wy2C&,$D  0z    % @5 ,$D  0a p    ,$D  0B  Z Do?"0  B   T DjJ?" AP B  Z DjJ?" A     `'A ?"p` G S2NAD+20 AK   T80A ?" U Z 2NADH+ 2H+4 0( AK    ` :A ?"0  vUDPG1"lv20 CC  Hv??"gw@ 0 0"  Hv??"w@ 0 0`  s *v"}  TGA v??"p  0 J$0G f   HQA "n  0 Xv U_$0G ,G B  s *޽h ? 1?Tz<%UӥaG|s k ___PPT10K .+D# '  = @B D' = @BA?%,( < +O%,( < +D' =%(D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*+  0L0    5 (    T|bA ?"K rj* PSv a|xWlyv (UDP-glucuronyl transferases, UGT)  _00 c g3 G3G3G3C6  (  TbA ?"P Y,$ 0 b>NO. Pg3 -z @    *  ,$D  0B  Z Do?"@    `~A ?"@  ]+ UDPGA:0 GWG3@z    % ZZ,$D  0   ` A ??"g      `HA ?" k  VZ$0 c     ` A ??"Pm w: 8 $@ 0   `XA ?"< , ,$ 0 D+ UDP"0 CH  T`A ?"f ,$ 0 a|x60 ccH  0޽h ? 1?Tz<%UӥaG|___PPT10+i[>wD '  = @B D' = @BA?%,( < +O%,( < +D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B-randombar(horizontal)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =%( D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(++0+0 ++0+ 0 ++0+ 0 +4  0L0   0\ (  @z    p'a ,$D  0   `hA ?"  V̖n$0 c    ` A ??"  x  c $8A Z   A    s *A  )b A  &xno   `A ?"  `* PSv kxxlyv (sulfate transferase )  _*0 _Pcg3G3 g 3 g 3 g 3 G$   02   `A ?" =/ ,$ 0 `>NO. _g3 &z P `     ?  ,$D  0    `A ?"P `  \ PAPS60 CG3B   T D?"P    `hA ?"  ,$ 0 B+PAP"0 C4   fB ?"1 )Q,$ 0 \ ̖nkxxo$0 c    ` A ??"" I+8 $@ 0H  0޽h ? 1?Tz<%UӥaG|___PPT10+SFD '  = @B D' = @BA?%,( < +O%,( < +D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B-randombar(horizontal)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-s6Bwipe(left)*<3<* D' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =%( D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(++0+0 ++0+ 0 ++0+ 0 +   0L0   @ @ (  ~  s *TB    B  ~  s *x"B ~ ]  B     ` A  ??"!gX  l  T-B ?"`Z |_p YNpvA YNp_p vA??$R  T9B ?"IIC js'l 7u S-N"l7u66+ ^  c 6A7IQu~TS^6 9  Hv??"gw@! 0 0"  Hv??"w@" 0 0`  s *v"}  TFB v??"p # 0 J$0G f   H,PB "n $ 0 Xv U_$0G ,G b  JA޽h ?10+ 1?Tz<%UӥaG|___PPT10e.+D='  = @B +O   0L0 $  P  (    c $^B '~<$ 0  B  :  ZTeB ?"<'n ,$  0 n5. u(lx~TS^$ 0  c @z fK   WS,$D 0   `pB ?"fT 2  hƀx u(lx $ 0  c B  Z Do?"    `8zB ?" K  Zu(lƀx$0 c    ` A %??"%  8 %$D 0  TB ?" ,$ 0 x<\KQp N-2uW<\KQp==4  6B  `*$ 0v0___PPT106___PPT9 *2uWvOSOS - z2ukx(lx(SAM)Bhigg3$H  0޽h ? 1?Tz<%UӥaG|___PPT10.+ZnD' B = @B D~' = @BA?%,( < +O%,( < +D' =%(%(D' =%(D>' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-m6Bbox(in)*<3<*D' =%(D3' =4@BBB B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bbox(out)*<3<*D-' =%(D#' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*D' =%(DR' =4@BBBB%(D' =1|:Bvisible*K3>+B#style.visibility%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*53>B ppt_xD' =+4 8?\CB#ppt_yBCB#ppt_yB*53>B ppt_yD' =%(D' =%(D]' =4@BBBB%()))D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-i6B wedge*<3<*D' =%(Dj' =A@BBBB0B%()))D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-i6B wedge*<3<* ++0+0 ++0+0 ++0+ 0 +R   0L0 |t` (    c B 0e0e "I <$ 0 B     fB ?"_a  B  H  0޽h ? 3ur3f}}f^___PPT10>.+lD'  = @B D' = @BA?%,( < +O%,( < +D' =%(%(D' =%(DP' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B#blinds(vertical)*<3<*D' =%(DP' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*#%(D' =-6B#blinds(vertical)*<3<*#+8+0+0 +/  0L0 2*p(    HB  z5   B    TB ?"6 v  T"Metabolism of Bile and Bile Acids## H  0޽h ? 3ur3f}}___PPT10e.+D='  = @B +  0L0    . (  F @hb  *N   @XB  Z DjJ?"P0 0   `B ?"  ZƀS|~$0 c    `B ?" XRl$0 c    fLB ?"  ZƀVSm)$0 c    `B ?"Xb p (ƀAl)(0 g3    `C ?" hb r (ƀVƀAl)(0 g3  TC ?" I ,$  0 0 ;N g:gbR ƀAlxv(+Tϑgؚ)0Yyv{|I{^0 0 cg3 c. kk~  s * C Tw  C  H  0޽h ? 1?Tz<%UӥaG|___PPT10d+D'  = @B D' = @BA?%,( < +O%,( < +D' =%(D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-6B%strips(downRight)*<3<* +8+0+ 0 +w   0L0 ~(    Zt C ?" bƀAlx(bile acids)vi_ ƀAlx/fX[(WNƀAl-NN'Y{|ƀpxv;`y Nvbvvb__X[(W sSƀAlxv {yƀv (bile salts)0h00n908xg3g36c, /  0q6   fL)C ?"+ #  *N ƀAlxvR{| c~gR  00x 5x G !c cgcrL  ^ 7 #  r   ` o?"  .   `=C ?"^   *8nyƀAlx(free bile acid)(0 g3:   `GC ?"PP 7 6~TƀAlx(conjugated bile acid)(0 g3  # lQC ?"d   C  H  0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D='  = @B + 0L0    (    TXC ?"  H"0 C  4   f,cC ?" 8,$D 0 \ 8nyƀAlx$0 c Dz p99  ]*p,$D  0   ` A &??"p9 &   `pnC ?"l9 ZOƀx$0 c    `xC ?"W H"0 C    fC ?"` H"0 C ,z 0    nq,$D  0    `C ?"9 BCOOH"0 CN p0    p0 @ 0 n   p`0 ,$D  0    ` A '??"0 n '   fC ?" A H"0 C     fC ?"` E  `OE1'lƀx$0 c H  0޽h ? 1?Tz<%UӥaG|D < ___PPT10 +D '  = @B D ' = @BA?%,( < +O%,( < +D' =%(%(D' =%(D@' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bdissolve*<3<*D' =%(D[' =4@BBBB%(E' =1B B`BPB1:Bhidden*3>+B#style.visibility= `B<*D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(down)*<3<*D' =%(D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-s6Bwipe(down)*<3<* +8+0+0 +  0L0    u (  4   fXC ?"1x,$ 0 \ ~TƀAlx$0 c .z  o;  _,$D  0T Y #  o;t   `C ?" CONHCH2CH2SO3H0 GOGOGOG   ` A (??"Y (    fC ?"p   ^ O[rxƀx$0 c z  t;   0,$D  0    `C ?"@ G  ^ Ou(lƀx$0 c 5N Y    t;    `C ?" w CONHCH2COOHP 0 GOG    ` A )??"Y )H  0޽h ? 3ur3f}}  ___PPT10 +'DL '  = @B D ' = @BA?%,( < +O%,( < +D>' =%(%(D' =%(D@' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bdissolve*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(down)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(down)*<3<*+8+0+0 +" 0L0   (  F >E/  u<   `C ?">  cegnR^5 Ccgc r   ` o?"A`@   `$D ?" 0R~ƀAlx(primary bile acid)40 cCD   ` D ?"E/ 4!k~ƀAlx(secondary bile acid)40 cC  ZD ?"T ,$D 0 \R~ƀAlx /f~ހNƀV:NSevcTbvƀAlx Sbƀx0E1'lƀxSv^~TWƀAlx0P00x)00xg3)c / 0q6  Z$ D ?"s ,$D  0 \!k~ƀAlx (WS~̃\O(u NR~ƀAlx 7-W1'lTubvƀAlx Sb1'lƀxSwƀx0P00x)00xg3)c 0q6H  0޽h ? 1?Tz<%UӥaG|___PPT10+,D'  = @B D' = @BA?%,( < +O%,( < +D' =%(D' =%(D@' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bbox(out)*<3<*D' =%(D' =%(D>' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-m6Bbox(in)*<3<*+p+0+0 ++0+0 +t 0L0 ~ v  (  Bz M    ,$D  0B  Z Do?"    # l(9D ?"M+   f7-W1'l"0 CFz @  @,$D  0   ` A *??"@p *   fED ?" 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'=  \*Function of Liver in Material Metabolism ++ H 0 0޽h ? 3ur3f}}y___PPT10Y+D=' = @B +  K0 4x(  4 4 s *+@_E + *6GHI` 4 Z+?" :c,$ 0 >|_u0 |SvTbNR0 |u_ ( vF2 # 4 4 ZȚ+?"/ ,$ 0 hV~QۏLN|N"_&3 H 4 0޽h ? 1?Tz<([ӥaG|I A ___PPT10! +ՁD' = @B DP' = @BA?%,( < +O%,( < +D{' =%(D#' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*4%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*4D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*4D' =%(D' =%(DT' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*4%(D' =-6B'blinds(horizontal)*<3<*4+p+0+4+ ++0+4+ + K0 8T(  8~ 8 s *+ @\F  +  8 c $@] + *ppqrsH 8 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +  K0 `X<(  <~ < s *l& @$G~f  &  < c $l&@2Y<$ 0 & 0$%&b < Z&?" :\O(u(W{|vmS08T6e0Tb0RNЏGWwQ g͑\O(u0D8vFx2g3c MM//H < 0޽h ? 1?Tz<%UӥaG|___PPT10.+Dv' = @B D1' = @BA?%,( < +O%,( < +Dh' =%(D' =%(DX' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*<%(D' =-6B+checkerboard(across)*<3<*<DX' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*<a%(D' =-6B+checkerboard(across)*<3<*<a+8+0+< + K0 @(  @ @ s *x!& @\F<$  0  &  @ c $'&@bY<$  0 & *"#$H @ 0޽h ? 1?Tz<%UӥaG| ___PPT10.+/.DL' = @B D' = @BA?%,( < +O%,( < +D>' =%(%(D' =%(D>' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-m6Bbox(in)*<3<*@D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-6B%strips(downRight)*<3<*@DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-6B%strips(downRight)*<3<*@D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@%(D' =-6B%strips(downRight)*<3<*@DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@3%(D' =-6B%strips(downRight)*<3<*@3D' =%( DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@36%(D' =-6B%strips(downRight)*<3<*@36DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@6Q%(D' =-6B%strips(downRight)*<3<*@6QD' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@QT%(D' =-6B%strips(downRight)*<3<*@QTDR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*@Tr%(D' =-6B%strips(downRight)*<3<*@Tr+p+0+@ ++0+@ +  K0 D(  D D s *0B& @%_<$D 0  &  D c $\H&@/7Y<$  0 & &xW | }H D 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B + K0  Hv(  H~ H s *h~ @\}  ~  H c $Z&@,<$  0 ~  0EH H 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +c K0 &0L(  L~ L s *k& @ls  &  L s *$r&@] <$  0 & (yMNOP* L ZՁ?" 5 ,$ 0 ^* ;Ne_uirlS # H L 0޽h ? 1?Tz<%UӥaG|  ___PPT10 .+IxD ' = @B D ' = @BA?%,( < +O%,( < +D|' =%(%(D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*L %(D' =-6B%strips(downRight)*<3<*L DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*L =%(D' =-6B%strips(downRight)*<3<*L =D{' =%(D#' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*L%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*LD' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*L+p+0+L ++0+L +0 K0 ?7@P(  P P Hh& @zf   &  P  `&?"  +  U#Biotransformation Function of Liver$$ H P 0޽h ? 3ur3f}}y___PPT10Y+D=' = @B +M K0 \TPT(  T~ T s *& @ %i  &  T s *D&@=R  & (yMNOPF F  T p m r T  f jJ?? #,$D 02 T  `& ?? F  ,$D 0 fQn'`Yo }0{|I{" 0 c  2 T  `& ?? f ,$D 0 fYn'`Yoir0kirI{" 0 c   T T&?" t  ^ ^%{Qir(& vF" H T 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +K0 \T`X(  X X T0P ??w ,$ 0  uirlSvaIN [SOQv^%{Qir(ۏLlS OvQmp;m (inactivate) bk(detoxicate)f:N͑v/fSOُNir(vn㉦^XR fNcQSOY0  0e0 g3c cc ccg3P  5 0q6 X T@P ??j,7,$ 0 T uirlSv;N:W@b /f;NhV[ FO(W00ÀSTv_N gN[uirlSR 0J 0 0x g3 c + 0q6F X TxBP ??f ,$  0  ; vuirlS\O(u`"k\O(u&0g3$H X 0޽h ? 1?Tz<%UӥaG|. & ___PPT10 +חoDB ' = @B D ' = @BA?%,( < +O%,( < +D*' =%(%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*X%(D' =-6B-randombar(horizontal)*<3<*XD' =%(D' =%(DV' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*X%(D' =-6B)randombar(vertical)*<3<*XD' =%(D' =%(DD' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*X%(D' =-s6Bwipe(left)*<3<*X++0+X& ++0+XP ++0+XP +<  K0 p\~(  \~ \ s *NP @(/  P  \ s *hWP@ P (789d \ Z\?"C7o ,$D 0 .* gNir(~Ǐ,{NvS^sSSz)RcQSOY0<0vffZcc  \ Z_P?" dB,$D 0 h* ir(sSO~Ǐ,{NvS^T g'`9eSN N'Y _{NgNg'`f:_vir(~T, sS,{NvS^ Mbg~cQ0,58vffn5c% H \ 0޽h ? 1?Tz<%UӥaG|___PPT10+[D*' = @B D' = @BA?%,( < +O%,( < +D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*\%(D' =-6B-randombar(horizontal)*<3<*\D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*\%(D' =-6B-randombar(horizontal)*<3<*\+p+0+\ ++0+\P +e K0 tl`(  ` ` BrP @\Y)  P . `  xP0e0ejJ @C"?]Y P *H ` 0޽h ? 3ur3f}}y___PPT10Y+D=' = @B +]K0 \Td(  d d H~ (?"7JY  .j; W,gyrp vco;m'lRP[ vQ-NN*N'lSP[ReQ^irRP[-N SN'lSP[؏S:N4l EeSy:NmTR'lSv0v08200cc'c g35pH d 0޽h ? 3ur3f}}___PPT10i._g+D=' = @B + K0 @8h(  h h C $A RUS'lv|T,$D  0 h Hv??"gw@U 0U 0" h Hv??"w@U 0U 0` h s *v"} h T$jPv??"p  U 0 J$0G f  h HOP"n  U 0 Xv U_$0G ,G B h s *޽h ? 1?Tz<%Uӥf|___PPT10+EpUhD' = @B D_' = @BA?%,( < +O%,( < +D' =%(%(D' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*h%(D' =+4 8?dCB2/3*#ppt_wBCB#ppt_wB*Y3>B ppt_w<*hD' =+4 8?dCB2/3*#ppt_hBCB#ppt_hB*Y3>B ppt_h<*h+K0  l(  l l NP ?"7 L&0 2G+Y x l NTP ?" ,$D 0 " NirSirbs'lSir >NOh0u(Z2g3 cg3c xB l BD?"P l  ` A ??"    l  `pP?"F <  l  `4P?"   J"  l  `P?" `   P [(lWZ" b l JA޽h ?10+ 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +K0 &p(  px p <A ??i  p HP>B# nYspvu irlSǏ z( 0 g  p Hv??"gw@U 0U 0" p Hv??"w@U 0U 0` p s *v"} p TlPv??"p  U 0 J$0G f  p H0P"n  U 0 Xv U_$0G ,G B p s *޽h ? ffD3fy___PPT10Y+D=' = @B + K0   t(  t t HP?"d X2. ~|SOUS'lSv| US'lSv( monoamine oxidase, MAO)N 0  00x c g3,  t HP?"}7w  X[(WMO~|SOQ> u(g3c  t HX?"p7  , PSvS^ PS{|'lS1(lWubv^v u( (cg3cg3 cg3 'F    t    t TЁ?" U  /RCH2NH2+O2+H2O20 cg3o3g3o3ckckckcB t Z DjJ?"m V ` V ` t ThY?#" `    RCHO+NH3+H2O 0 cg3ckckcH t 0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +K0 x(  x x HPe?" ~3. 1"lvS1"lv|&00c   x N\?"d   X[(WMOހm-NP u(cg3c F x N?"2d'  PSvS^ 1"lv(alcohol dehydrogenase, ADH)PS{|'lSb0 1"lv(aldehyde dehydrogenase, ALDH)PS{|ubx0d0u(x*0u(x+00xcg3cC c  g 3 c  g 3 c " c  c  g 3 c  g 3 c d    pKKH x 0޽h ? 3ur3f}}___PPT10i._Y+D=' = @B +  K0 |(  | | c $@ <$ 0  &x  } |  `?" 7 T ,$ 0  N 4lS^ Yy4lv{|V0vFP0vFG !"  nnH | 0޽h ? 1?Tz<%UӥaG|y q ___PPT10Q .+CD' = @B Dt' = @BA?%,( < +O%,( < +D' =%(%(D#' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*|%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*|D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*|D' =%(D' =%(DX' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*|%(D' =-6B+checkerboard(across)*<3<*|+p+0+|~ ++0+|~ +K0 RJ(    N?"PdF ,$  0 `~T[aQ+T gW0Wb(lWvoir0kirbo }GWSSu~TS^ ,10 uZ21c 1 SS  N ?"c d# ,$  0 l~TBRa|x0kxx07u0u(lx0YNpW02uWI{ir(bWV f70 uZx2cg3c#c 7 <  Z8?" ,$  0 pV ~TS^4G !g ! H  0޽h ? 3ur3f}}  ___PPT10 ._a>D+KPD ' = @B D ' = @BA?%,( < +O%,( < +D' =%(%(D' =%(DN' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-}6B!slide(fromLeft)*<3<*D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B%strips(downRight)*<3<*D' =%(D' =%(DP' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B#strips(downLeft)*<3<*++0+ ++0+ ++0+ +" K0 ? 7  (  x  c $|L@         !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}   s *R@7<$ 0  *qklm  c ,Awy1T,$D  0  c ,A wy2C&,$D  0z    % @5 ,$D  0a p    ,$D  0B  Z Do?"0  B   T DjJ?" AP B  Z DjJ?" A     `P?"p` G S2NAD+20 AK   T ?" U Z 2NADH+ 2H+4 0( AK    `?"0  vUDPG1"lv20 CC  Hv??"gw@U 0U 0"  Hv??"w@U 0U 0`  s *v"}  Tv??"p  U 0 J$0G f   H "n  U 0 Xv U_$0G ,G B  s *޽h ? 1?Tz<%UӥaG|s k ___PPT10K .+D# ' = @B D' = @BA?%,( < +O%,( < +D' =%(D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*+ K0    5 (    T?"K rj* PSv a|xWlyv (UDP-glucuronyl transferases, UGT)  _00 c g3 G3G3G3C6  (  T?"P Y,$ 0 b>NO. Pg3 -z @    *  ,$D  0B  Z Do?"@    `-?"@  ]+ UDPGA:0 GWG3@z    % ZZ,$D  0   ` A ??"g      `2?" k  VZ$0 c     ` A ??"Pm w: 8 $@ 0   `x6?"< , ,$ 0 D+ UDP"0 CH  T:?"f ,$ 0 a|x60 ccH  0޽h ? 1?Tz<%UӥaG|___PPT10+i[>wD ' = @B D' = @BA?%,( < +O%,( < +D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B-randombar(horizontal)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =%( D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(++0+ ++0+  ++0+  +: K0   0b (  @z    p'a ,$D  0   `7?"  V̖n$0 c    ` A ??"  ~  s *;@      s *A@ )b  &xno   `8H?"  `* PSv kxxlyv (sulfate transferase )  _*0 _Pcg3G3 g 3 g 3 g 3 G$   02   `|[?" =/ ,$ 0 `>NO. _g3 &z P `     ?  ,$D  0    `_?"P `  \ PAPS60 CG3B   T D?"P    `,c?"  ,$ 0 B+PAP"0 C4   fLg?"1 )Q,$ 0 \ ̖nkxxo$0 c    ` A ??"" I+8 $@ 0H  0޽h ? 1?Tz<%UӥaG|___PPT10+SFD ' = @B D' = @BA?%,( < +O%,( < +D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B-randombar(horizontal)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(left)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-s6Bwipe(left)*<3<* D' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =%( D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(++0+ ++0+  ++0+  +  K0   @ @ (  ~  s *@%    ~  s *|@p ]      ` A  ??"!gX  l  TH?"`Z |_p YNpvA YNp_p vA??$R  T@?"IIC js'l 7u S-N"l7u66+ ^  c 6A7IQu~TS^6 9  Hv??"gw@!U 0U 0"  Hv??"w@"U 0U 0`  s *v"}  T[~v??"p # U 0 J$0G f   H^~"n $ U 0 Xv U_$0G ,G b  JA޽h ?10+ 1?Tz<%UӥaG|___PPT10e.+D=' = @B +O  K0 $  P  (    c $|@'~<$ 0   :  Z<?"<'n ,$  0 n5. u(lx~TS^$ 0  c @z fK   WS,$D 0   `?"fT 2  hƀx u(lx $ 0  c B  Z Do?"    `<?" K  Zu(lƀx$0 c    ` A %??"%  8 %$D 0  Tp?" ,$ 0 x<\KQp N-2uW<\KQp==4  6P `*$ 0v0___PPT106___PPT9 *2uWvOSOS - z2ukx(lx(SAM)Bhigg3$H  0޽h ? 1?Tz<%UӥaG|___PPT10.+ZnD' = @B D~' = @BA?%,( < +O%,( < +D' =%(%(D' =%(D>' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-m6Bbox(in)*<3<*D' =%(D3' =4@BBB B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bbox(out)*<3<*D-' =%(D#' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*D' =%(DR' =4@BBBB%(D' =1|:Bvisible*K3>+B#style.visibility%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*53>B ppt_xD' =+4 8?\CB#ppt_yBCB#ppt_yB*53>B ppt_yD' =%(D' =%(D]' =4@BBBB%()))D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-i6B wedge*<3<*D' =%(Dj' =A@BBBB0B%()))D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-i6B wedge*<3<* ++0+ ++0+ ++0+  +^  K0 `(     s 0e0e @"c <$ 0    # l|?@"5 [   H  0޽h ? 3ur3f}}f^___PPT10>.+lD' = @B D' = @BA?%,( < +O%,( < +D' =%(%(D' =%(DP' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B#blinds(vertical)*<3<*D' =%(DP' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*#%(D' =-6B#blinds(vertical)*<3<*#+8+0+ +/ K0 2*p(    H @z5      T?"6 v  T"Metabolism of Bile and Bile Acids## H  0޽h ? 3ur3f}}___PPT10e.+D=' = @B + K0    . (  F @hb  *N   @XB  Z DjJ?"P0 0   `0?"  ZƀS|~$0 c    `?" XRl$0 c    f?"  ZƀVSm)$0 c    `?"Xb p (ƀAl)(0 g3    `4?" hb r (ƀVƀAl)(0 g3  T?" I ,$  0 0 ;N g:gbR ƀAlxv(+Tϑgؚ)0Yyv{|I{^0 0 cg3 c. kk~  s *@5u   H  0޽h ? 1?Tz<%UӥaG|___PPT10d+D' = @B D' = @BA?%,( < +O%,( < +D' =%(D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-6B%strips(downRight)*<3<* +8+0+  +}  K0 (    Z?" bƀAlx(bile acids)vi_ ƀAlx/fX[(WNƀAl-NN'Y{|ƀpxv;`y Nvbvvb__X[(W sSƀAlxv {yƀv (bile salts)0h00n908xg3g36c, /  0q6   f?"+ #  *N ƀAlxvR{| c~gR  00x 5x G !c cgcrL  ^ 7 #  r   ` o?"  .   `H?"^   *8nyƀAlx(free bile acid)(0 g3:   `?"PP 7 6~TƀAlx(conjugated bile acid)(0 g3  3 r\ ?@"$d    H  0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +K0    (    T?"  H"0 C  4   f?" 8,$D 0 \ 8nyƀAlx$0 c Dz p99  ]*p,$D  0   ` A &??"p9 &   `p?"l9 ZOƀx$0 c    `!?"W H"0 C    f?"` H"0 C ,z 0    nq,$D  0    `?"9 BCOOH"0 CN p0    p0 @ 0 n   p`0 ,$D  0    ` A '??"0 n '   f+?" A H"0 C     f$0?"` E  `OE1'lƀx$0 c H  0޽h ? 1?Tz<%UӥaG|D < ___PPT10 +D ' = @B D ' = @BA?%,( < +O%,( < +D' =%(%(D' =%(D@' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bdissolve*<3<*D' =%(D[' =4@BBBB%(E' =1B B`BPB1:Bhidden*3>+B#style.visibility= `B<*D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(down)*<3<*D' =%(D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-s6Bwipe(down)*<3<* +8+0+ + K0    u (  4   f+?"1x,$ 0 \ ~TƀAlx$0 c .z  o;  _,$D  0T Y #  o;t   `+?" CONHCH2CH2SO3H0 GOGOGOG   ` A (??"Y (    fm+?"p   ^ O[rxƀx$0 c z  t;   0,$D  0    `Y+?"@ G  ^ Ou(lƀx$0 c 5N Y    t;    `(G+?" w CONHCH2COOHP 0 GOG    ` A )??"Y )H  0޽h ? 3ur3f}}  ___PPT10 +'DL ' = @B D ' = @BA?%,( < +O%,( < +D>' =%(%(D' =%(D@' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bdissolve*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(down)*<3<*D' =%(D7' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-s6Bwipe(down)*<3<*+8+0++ +"K0   (  F >E/  u<   `+?">  cegnR^5 Ccgc r   ` o?"A`@   `+?" 0R~ƀAlx(primary bile acid)40 cCD   `x+?"E/ 4!k~ƀAlx(secondary bile acid)40 cC  Zg+?"T ,$D 0 \R~ƀAlx /f~ހNƀV:NSevcTbvƀAlx Sbƀx0E1'lƀxSv^~TWƀAlx0P00x)00xg3)c / 0q6  Zlh+?"s ,$D  0 \!k~ƀAlx (WS~̃\O(u NR~ƀAlx 7-W1'lTubvƀAlx Sb1'lƀxSwƀx0P00x)00xg3)c 0q6H  0޽h ? 1?Tz<%UӥaG|___PPT10+,D' = @B D' = @BA?%,( < +O%,( < +D' =%(D' =%(D@' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bbox(out)*<3<*D' =%(D' =%(D>' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-m6Bbox(in)*<3<*+p+0+~ ++0+~ +tK0 ~ v  (  Bz M    ,$D  0B  Z Do?"    # l(?+?"M+   f7-W1'l"0 CFz @  @,$D  0   ` A *??"@p *   fTr+?" G Vƀx$0 c Jz P M  P M,$D 0    ` A +??"P M +    fv+?" ) Z1'lƀx$0 c   Tz+?"q T R~ƀAlxc   Ty+?"Q Pw  T !k~ƀAlxc   Hv??"gw@,U 0U 0"  Hv??"w@-U 0U 0`  s *v"}  T+v??"p . U 0 J$0G f   H(J+"n / U 0 Xv U_$0G ,G B  s *޽h ? 1?Tz<%UӥaG| ~ ___PPT10^ +6(DB ' = @B D ' = @BA?%,( < +O%,( < +D' =%(D' =%(D1' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-m6Bbox(in)*<3<*DK ' =%(DH' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D#' =+4 8?nCB!#ppt_x-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*D' =+4 8?RCBBCB#ppt_wB*Y3>B ppt_w<*D' =+4 8?\CB#ppt_hBCB#ppt_hB*Y3>B ppt_h<*D' =%(DK' =4@BBB B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B+checkerboard(across)*<3<*+FK0   8 (  bz T   0 |` , $D  0B  Z Do?"  8  # l(+?"T  7-W1'lB0 CCCLz p  p,$D  0   ` A 0??"p 0   f+?"  \ E1'lƀx$0 c Hz p  p,$D 0    ` A 1??"p 1    f+?" $  Xwƀx$0 c   Th+Ɖ?" Pw T !k~ƀAlxc   T4+?"q T R~ƀAlxc   Hv??"gw@2U 0U 0"  Hv??"w@3U 0U 0`  s *v"}  T+v??"p 4 U 0 J$0G f   Hԩ+"n 5 U 0 Xv U_$0G ,G B  s *޽h ? 1?Tz<%Uӥf|4 , ___PPT10 + D ' = @B D ' = @BA?%,( < +O%,( < +D' =%(D' =%(D1' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-m6Bbox(in)*<3<*D' =%(D' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =+4 8?RCBBCB#ppt_wB*Y3>B ppt_w<*D' =+4 8?RCBBCB#ppt_hB*Y3>B ppt_h<*D' =%(DG' =4@BBB B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B'blinds(horizontal)*<3<*+ K0 8(     `$+?" H"0 C ,  T,+?"< ,$D 0 fN ƀAlxvN"& 0  G !   T+?"  ,$D 0 .F1. R~ƀAlxvub aMO~ހvހmT_|SO-N aSeƀV 4040 c c g3cg36   Zd~?"  ,$D  0 L; ƀVlSbƀAlx/fvQ(WSOQN"v;NS aPvƀV7-Sv b4 24 2cg3c6H  0޽h ? 1?Tz<%UӥaG|___PPT10d+_J$D' = @B D' = @BA?%,( < +O%,( < +D' =%(D' =%(DR' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B%strips(downRight)*<3<*+8+0++ +.K0    ~ (  F  Tԅ?"}$,$D 0 ƀV(27C): 0 cg30  T?"> ^Y ,$D 0 j7-SƀV$ 0  c 0 @ @ #   ,$D  0B  Z Do?"0 @ @B  Z Do?"@ @ @\   f?">  ,$D 0 R~ƀAlx(24C): 0 cg3B  Z Do?"   ,$D  0.  Z\?" ",$D 0 b~TWR~ƀAlx$ 0  c z @   #  - ,$D  0B   Z Do?"@ @ ,$D  0    f?"p  j 7-Sv(40Zc  Zh?" 7 p Ǐ z<3g3c H  0޽h ? 3ur3f}}j"b"___PPT10B"+/DF!' = @B D!' = @BA?%,( < +O%,( < +D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B-randombar(horizontal)*<3<*D' =%(DH' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =+4 8?\CB#ppt_xBCB#ppt_xB*Y3>B ppt_x<* D#' =+4 8?nCB!#ppt_y-#ppt_h/2BCB#ppt_yB*Y3>B ppt_y<* D' =+4 8?\CB#ppt_wBCB#ppt_wB*Y3>B ppt_w<* D' =+4 8?RCBBCB#ppt_hB*Y3>B ppt_h<* D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B-randombar(horizontal)*<3<*D' =%(DH' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D#' =+4 8?nCB!#ppt_x-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*D' =+4 8?RCBBCB#ppt_wB*Y3>B ppt_w<*D' =+4 8?\CB#ppt_hBCB#ppt_hB*Y3>B ppt_h<*D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B-randombar(horizontal)*<3<*D' =%(DH' =%(D' =4@BBBB%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =+4 8?\CB#ppt_xBCB#ppt_xB*Y3>B ppt_x<*D#' =+4 8?nCB!#ppt_y+#ppt_h/2BCB#ppt_yB*Y3>B ppt_y<*D' =+4 8?\CB#ppt_wBCB#ppt_wB*Y3>B ppt_w<*D' =+4 8?RCBBCB#ppt_hB*Y3>B ppt_h<*D ' =%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<* %(D' =-6B-randombar(horizontal)*<3<* ++0+ ++0+ ++0+ ++0+  +K0  (  "   f?" ~ 2. !k~ƀAlxvubN_s(40xc $  ZL?"p aMO\ NkT'Y aǏ z&00c$    f?"c *  \ R~ƀAlx$0 c    f?"c   \ !k~ƀAlx$0 c F      4 B  Z Do?"p p   ` ū?"`  g Ṽ$0 c     ` ɫ?"\  Z4l1$0 c H  0޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +CK0 RJ (  <  Tϫ?"Md "ƀAlx_s ƀAlx_si_Z40 0g3 g3 f  Tޫ?"72  hƀAlxƀAlceQTT Ǐ͑8T6e~Y SV0R (WQlS:N~TWƀAlx ~ƀSQ!kceQTvǏ z0(5405c 5044H  0޽h ? 3ur3f}}y___PPT10Y+D=' = @B + K0 0 (   F   b  c 2Agan Y6R  <  XƀV$0G `B B 0DԔwz$  <M <~TƀAlx Tb0.4~0.6g/d N"`l3~5g/d $0G,     T?"S zƀAlx_svǏ z& 3 &3  RR  Hv??"gw@6U 0U 0"  Hv??"w@7U 0U 0`  s *v"}  T8v??"p 8 U 0 J$0G f   H4"n 9 U 0 Xv U_$0G ,G B  s *޽h ? 1?Tz<%UӥaG|y___PPT10Y+D=' = @B +K0 TL@(    TE?"@ ,$D  0 R ƀAlx_svutaIN \ gPvƀAlxS Y)R(uNnNSO[ƀAlxvut0R 300g3c * 0q6H  0޽h ? 1?Tz<%UӥaG|-%___PPT10+EpUhD' = @B Dl' = @BA?%,( < +O%,( < +D' =%(%(D+' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =+4 8?dCB2/3*#ppt_wBCB#ppt_wB*Y3>B ppt_w<*D' =+4 8?dCB2/3*#ppt_hBCB#ppt_hB*Y3>B ppt_h<*+8+0+ +P K0 "P(    s *U@<$D 0     TF?"g,$D  0 81.Oۏ{|vmSN8T6e zSOgW  N4lNu4l$N*NObP 40n40n c c.  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+B#style.visibility<*%(D' =+4 8?dCB0-#ppt_w/2BCB#ppt_xB*Y3>B ppt_x<*D' =+4 8?\CB#ppt_yBCB#ppt_yB*Y3>B ppt_y<*D' =%(D' =A@BBBB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =+4 8?RCBBCB#ppt_wB*Y3>B ppt_w<*D' =+4 8?RCBBCB#ppt_hB*Y3>B ppt_h<*D' =%(D' =%(DV' =A@BBB*B0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B)barn(outHorizontal)*<3<*++0+F ++0+F ++0+F +mK0 `x(  .   `@F?"i),$D 0 \u4lO(0 g3 *   `F?"h ey ,$D 0 XN4lO$0 c    ` A :??"jd 8 :$D  0   `F?"V # w  \u(lƀxvzSOgW &W H  0޽h ? 3ur3f}}  ___PPT10 +j}mDa ' = @B D ' = @BA?%,( < +O%,( < +DS' =%(%(D' =%(DC' =4@BBB B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-6B#strips(downLeft)*<3<*D' =%(D@' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bdissolve*<3<*D' =%(D@' =A@BB BB0B%(D' =1:Bvisible*o3>+B#style.visibility<*%(D' =-o6Bdissolve*<3<*+p+0+F ++0+F +@ K0 C;p(    HF @i   F    `LF?"6 'L  Y'Metabolism of Bile Pigment and Jaundice(( H  0޽h ? 3ur3f}}___PPT10e.+D=' = @B + K0 PH(    s *F@2D( <$ 0 F ,,l ?  6F/  p ƀr }vi_.0vFZG$3H  0޽h ? 1?Tz<%Uӥf|___PPT10.+O9D8' = @B D' = @BA?%,( < +O%,( < +D*' =%(%(D' =%(DZ' =A@BBB B0B%(D' =1:Bvisible*o3>+B#style.visibility<*7%(D' =-6B-randombar(horizontal)*<3<*7+8+0+F +K0 P(  l  Z5F?"  ,$ 0 p ƀ~ }(bilirubin)egn SOQv_SIUSTir  @~ˆ}v0~ˆ}v0~ހr }0Ǐ'lS"lvSǏ'lSirv000'00g3&3 G3g3 c  g 3 c @  pKK`  ZF?" dA ,$  0 *; ~80egp~~ހ-N@~ˆ}vvR0$0 c"<  ZF?" 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