经过评估,专家小组认为该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是非反刍动物物种氨基酸L-精氨酸的有效来源。为了使补充的L-精氨酸对反刍动物和非反刍动物同样有效,需要防止其在瘤胃中降解。部分原文报道如下:
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-arginine produced with Corynebacterium glutamicum KCCM 80387 as a nutritio
nal feed additive for all animal species (category: nutritio
nal additive; functio
nal group: amino acids, their salts and analogues; and category: sensory additives; functio
nal group: flavouring compounds). The production strain C. glutamicum KCCM 80387 is a genetically modified strain and raises no safety concerns. The FEEDAP Panel co
ncluded that the additive does not pose any safety co
ncern with regard to the production strain. The use of l-arginine produced by fermentation with C. glutamicum KCCM 80387 in feed as nutritio
nal additive or as flavouring compound is safe for the target species. The FEEDAP Panel has co
ncerns on the use of l-arginine in water for drinking. The use of l-arginine produced by fermentation with C. glutamicum KCCM 80387 in animal nutrition is co
nsidered safe for the co
nsumers and for the environment. As regards the safety for the user, l-arginine produced with C. glutamicum KCCM 80387 is not irritant to skin, and not a dermal sensitiser but is irritant to the eyes and respiratory tract. The additive l-arginine produced by fermentation with C. glutamicum KCCM 80387 is regarded as an efficacious source of the essential amino acid l-arginine for non-ruminant nutrition. For the supplemental l-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen. l-Arginine is also co
nsidered efficacious when used as a flavouring compound in animal nutrition.
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